Social interaction with rat exposed to constant light during lactation prevents depressive-like behavior induced by constant light in adulthood

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Social interaction with rat exposed to constant light during lactation prevents depressive-like behavior induced by constant light in adulthood

Circadian rhythm disruptions are often observed in depressed patients, and changes in the light/dark cycle promote depressive-like behavior in animal models. Prolonged exposure to constant light (LL) is known to lead to arrhythmicity of circadian locomotor activity and depressive-like behavior in rats. Interestingly, neonatal exposure to LL prevents both arrhythmicity and depressive behavior in...

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Increased anxiety-like behavior but no cognitive impairments in adult rats exposed to constant light conditions during perinatal development

BACKGROUND Shift-work is suggested to affect fetal development negatively. In particular, maternal hormonal disturbance arising from sleep deprivation or circadian rhythm changes may disturb fetal growth or lead to complications during pregnancy. Exposure to constant light is an environmental stressor that can affect the circadian system and has been shown to induce neurochemical and behavioral...

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Light and electron microscopic examination of pineal gland in rats exposed to constant light and constant darkness.

OBJECTIVE This study was aimed to examine the pineal gland of rats exposed to constant light and darkness at light and electron microscopic level. DESIGN For this purpose 18 male Wistar rats were used. Animals were divided into three groups. Rats in group I (Control) were kept under 12 hrs light: 12 hrs dark conditions. Rats in group II were exposed to constant darkness, while rats in group I...

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Alleviation of constant-light-induced photoreceptor degeneration by adaptation of adult albino rat to bright cyclic light.

PURPOSE To further test the hypothesis that light-adaptation-mediated photoreceptor protection works through inhibition of apoptosis by activation and/or upregulation of neuroprotective molecules. METHODS Albino rats were born and raised in 5-lux cyclic light (12 hours OFF and ON). At 8 weeks of age, animals were adapted to 400-lux cyclic light for different periods. Light damage was induced ...

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Light Orthogonal Networks with Constant Geometric Dilation

An orthogonal network for a given set of n points in the plane is an axis-aligned planar straight line graph that connects all input points. We show that for any set of n points in the plane, there is an orthogonal network that (i) is short having a total edge length of O(jT j), where jT j denotes the length of a minimum Euclidean spanning tree for the point set; (ii) is small having O(n) verti...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 2015

ISSN: 0304-3940

DOI: 10.1016/j.neulet.2014.12.042